Reduction in peripheral blood K cells and activated T cells in primary biliary cirrhosis.

نویسندگان

  • G P Sandilands
  • R N Macsween
  • K G Gray
  • R J Holden
  • P Mills
  • F M Reid
  • M A Thomas
  • G Watkinson
چکیده

Lymphocyte subpopulations were measured in the peripheral blood of 13 patients with primary biliary cirrhosis (PBC), 13 with chronic active hepatitis (CAH), and 16 age- and sex-matched normal subjects. A significant, relative and absolute, reduction in activated T cells and K cells, compared with that in normal subjects, was found in PBC but not in CAH. The reduction in K cells observed in PBC was found to be accompanied by a parallel decrease in lymphocyte-mediated antibody-dependent cytotoxicity.

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عنوان ژورنال:
  • Gut

دوره 18 12  شماره 

صفحات  -

تاریخ انتشار 1977